WM-Cyclic-AMP Stimulator


  • The WMcAMP Stimulator is the first dedicated electrotherapy device that directly targets and boosts a key molecular signaling system inside cells that relays the messages to carry out metabolic activity for tissue healing and regeneration—the Cyclic AMP (cAMP) 'signal transduction pathway'.

  • Cyclic AMP (cAMP) is a major and key 'second messenger' molecule inside cells. Following injury, the cAMP molecules relay the messages to activate and continue metabolic events for tissue healing and regeneration, including gene expression.

Pain Signal Transmitted from the 'Voltage-Gated' Ion Channels Through the Pain Nerve Cell Walls

  • Pain occurs when pain nerve cells (specialized sensory neurons called 'nociceptors') are signalling along nerve fibres to the brain that injury exists or that there is danger of injury to tissues of the body. The outgoing pain signals start from the inside-to-outside 'voltage-gated' ion channels through the nociceptor cell walls.

'Voltage Gated' Ion Channels Through the Walls of 'Nociceptor' Pain Nerve Cells: Targets for cAMP Mediated Regulation.

  • By directly modulating the same cAMP 'signal transduction pathway', the WMcAMP Stimulator also decreases the overall activity and the specific electrical voltage across nociceptor wall ion channels—reducing or stopping the transmission of pain signals. Supporting research>

    The WMcAMP Stimulator does not "cover-up" the natural pain-generating process; it modulates the pain-generating conditions within the injured tissues—enhancing actual healing and regeneration.

    'Neuropathic' pain ('neuropathy') is caused by damage of nerves themselves from injury, surgery, disease or chemotherapy. The nerve tissue regeneration effects of modulating cAMP with chemical intervention have been extensively studied. The WMcAMP Stimulator is the first dedicated electromedical approach that can achieve this result. Supporting research>


  • Cyclic-A-M-P is produced within cells from the A-T-P molecule. A-T-P is called the "energy currency" of life, it functions like a rechargeable battery, and is the energy source that all cells need in order to do anything within the human body. In response to injury, A-T-P (ATP) is converted in a repeating cycle into cyclic-A-M-P (cAMP); the cAMP molecules then relay the specific messages to carry out the healing processes for the injury.

    At any time, the production of ATP and cAMP is limited by cellular chemical and energy supplies.

Cyclic AMP (cAMP) Second Messenger Activation in Response to Injury

  • The WMcAMP Stimulator precisely targets and gives an electrical energy boost that directly increases production of the cAMP molecule, and then directly increases the utilization of the cAMP messenger pathways activated in specific responses to the injury.

  • The WMcAMP Stimulator generates a repeating, timed, complex stimulation cycle that enhances and is in sync with the natural cAMP messenger pathway events inside the cells of the body.

    The powerful and beneficial effects of enhancing the cAMP messenger pathways for pain and injured tissue healing and regeneration, are well-studied biological and medical science. Supporting research>


  • The Woessner Malter Cyclic AMP (WMcAMP) Stimulator has been developed from special cooperation between American Physiatrist (pain and injury rehabilitation specialist physician) and Scientist, Doctor James Woessner MD PhD, and the Electromedicine Clinic in Melbourne, Australia. Dr. Woessner has pioneered and performed nearly 4000 noninvasive electrical nerve block treatments, which he recognized were simultaneously actually repairing damaged pain nerves via cAMP activation. Vita of Dr James Woessner MD PhD>

Damaged Nerve Fibers (red) Within a Nerve Bundle: Targets for cAMP Mediated Regeneration

  • The WMcAMP Stimulator is the result of data-based development, in parallel with laboratory equipment validation and clinical testing.

    The WMcAMP Stimulator has been designed for use by both clinicians and at home.


  • The healing process in response to an injury is fantastically complex, involving millions of cells. Each cell performs a unique and specialized function in the effort to repair and regenerate the injured tissues, in moment-by-moment constantly changing coordination with every other cell.

    We cannot know what each cell involved in the healing process is doing moment-by-moment; trillions of chemical reactions happen in the body every second, most of which are still unknown to medical science.

  • No two injuries are the same; every injury, even of the same anatomical structure, is a unique occurrence in each individual, requiring their body's precisely coordinated, unique healing response.

    Most electrotherapy devices for injury and pain treatments, transmit waveforms and frequencies into the body, in a non-targeted, "blanket" of electrical stimulation. Some cellular metabolic activities can be temporarily enhanced as a result, while at the same time, others can be negatively interfered with or completely inhibited.

    The WMcAMP Stimulator solves these electrotherapy problems by directly targeting and boosting what the body is already doing to heal and regenerate the damaged tissues (injury).


  • Pain neuron ('nociceptor') blockade—cAMP directly affects the electrical voltage across the pain nerve cell (neuron) 'voltage-gated' channels, so that neuropathic pain signals reduce or stop.

  • Relays the messages to begin and continue the metabolic activity for healing—including genetic expression.

  • Increases neuron and tissue survival and regeneration following injury.

  • Controls the ability of nerve cell 'axons' (sensing and movement signal conductors) to regenerate after injury.

  • Immune and non-immune system anti-inflammatory effects, giving immediate and long-term injured tissue protection.

  • Circulation enhancement, by blocking 'efferent' C-fiber type nerve signalling, resulting in vasodilation of local blood vessels.

  • Reduces muscle tension, and exerts central nervous system antispastic actions after injury.

  • Functional stimulation and regeneration of muscles and nerves.

  • Enhances whole brain and brain cell connection (synapse) plasticity following injury.


  • Advanced microcurrent electrotherapy. High precision, targeted stimulation of cellular 'second messenger' signalling molecules.

  • Neuropathic pain blocking. Decreases the overall activity, and the 'action potential' electrical voltage, of pain nerve cell 'voltage-gated' ion channels—reducing or stopping the transmission of pain signals.

  • Enhanced and faster injury healing. Gives extra electrical energy directly to the production and utilization of the 'cAMP' molecular 'messenger pathways' inside cells—that signal to start and continue the metabolic activity for healing, including gene expression.

  • Increased nerve cell ('neuron') and axon survival and regeneration after injury ('neuroregeneration'). Prevention of future neuropathic pain and loss of function.

  • Anti-inflammatory. Favorably modulates both immune and non-immune system inflammatory processes—protects injured tissues from chronic degradation.

  • Enhances circulation. Can also be applied effectively for wound and ulcer healing involving vascular disease/venous insufficiency.

  • Reduces muscle tension. Enhances function and regeneration of muscles following injury.

  • Improves whole brain response to injury. Enhanced brain cell connection ('synapse') plasticity after injury.

  • Noninvasive and no drug side effects. For clinic or home use.

  • Robust high-end componentry construction. Including external casing and connectors. Each unit is a precision electronics instrument, assembled, and individually programmed and tested by our engineers in our Australian factory. 5 year warranty.