FASTER WOUND HEALING

SIS W300ML ELECTROSTIMULATOR: AI POWERED WOUND HEALING



W300ML machine learning wound healing device


  • The SIS machine W300ML electrical stimulation device can be applied to most types of wounds:

    - Non healing and chronic wounds

    - Diabetic leg and foot ulcers

    - Infected wounds

    - Post surgical wounds (infected)

    - Trauma wounds

    - Venous stasis ulcers

    - Arterial ulcers

    - Pressure ulcers ('bedsores')

    - Necrotizing soft tissue infections


AI POWERED ELECTRICAL STIMULATION

AI machine learning algorithm electrical stimulation for wound healing


NEXT GENERATION AI WOUND HEALING

  • Older generation wound healing electrotherapy devices use non adaptive, fixed electrical stimulation, which is never specific or optimized to an individual wound.

    The SIS machine W300ML artificial intelligence machine learning technology repeatedly optimizes the electrical stimulation type and specifications for fastest healing of the specific wound that it is applied to.

    The W300ML continuously learns from its experiences and constantly improves its performance of healing the specific wound.

    The W300ML retains a long term memory of its wound healing experiences for up to 10 years, which it automatically applies to any wound it is applied to in the future.


STEM CELL WOUND HEALING EFFECTS

  • Targted stimulation of fibroblast cells in the wound to self-modify to have tissue regeneration abilities resembling stem cell potentials.

    These newly modified cells can form new tissues during the proliferative and remodeling phases of wound healing not normally possible.


CONTINUOUS WOUND MONITORING

  • Wound bioelectric and electrostimulation parameter data logging. Continuous wound monitoring provides an accurate assessment of rate and stage of individual wound healing.

    The SIS W300ML wound monitoring provides additional and supplementary information to the wound care professional, and can also be utilized for remote wound monitoring.


BIOELECTRIC WOUND HEALING

  • Electro-physiological and bioelectric wound healing dynamics are well established phenomenon:


  • The skin acts as an electrical battery. As a result of the normal, bidirectional 'pumping' of chemical ions through the skin layers, a constant electrical potential (voltage) of 10/20-50/70millivolts is permanently maintained across the skin, termed the transepidermal or transepithelial potential difference (TEP).



    Transepidermal Potential Difference



  • Intact skin has relatively high electrical resistance to the TEP. When skin layers are damaged or destroyed in any kind of wound, their electrical resistance to the TEP ‘skin battery’ immediately drops or disappears. The resulting TEP-generated electric field is electrically negative at the wound edges relative to the deeper tissues.


  • Many key cells involved in the healing response are sensitive to the TEP-generated electric field. The TEP electric field is the informational signal to these cells to move towards the wound surface, as well as for their differentiation, division and proliferation. These electric field-sensitive cell types include fibroblasts, chondrocytes, keratinocytes, endothelial cells, epithelial cells, mature macrophages and granulocytes.

    The TEP voltage through the wound is the key, local bioelectric controller of wound healing.


AI POWERED WOUND HEALING

  • Infection treatment. microenvironment-to-microorganism-type-specific, low intensity direct current. Effective for bacterial, viral and antibiotic resistant superbug infections.

  • Bioelectric healing. Realtime, self adaptive supplementation or replacement of the bioelectric controller of wound healing—the wound-generated electric field; boosts the natural 'current of injury'.

  • Accelerated healing. Targeted bio-signaling stimulation of intracellular 'second messenger' molecule pathways: cyclic-A-M-P and cyclic-G-M-P that relay and amplify the messages for metabolic activity and healing.

  • Better healing, less scar tissue. Stimulates the self-modification of fibroblast cells in the wound to have tissue regeneration abilities resembling stem cell potentials.

  • Reduces pain. Effects on: inflammatory mast cells, cross-talk between pain signaling nerve fibers, nociceptor ion channels that detect harmful stimuli, reducing the transmission of pain signals.

  • SIS electrodes do not contact wound. No discomfort or disturbance of new (granulation) tissue growth.

  • No drug side effects or risks. Quick and easy to apply. For home and in clinic use.

  • Artificial Intelligence (AI) machine learning. Repeated electrical stimulation optimization for each individual wound. Device learns how to heal each specific wound and continuously improves its function.

  • International Patent Application Pending device & technology.

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