WM-Cyclic-AMP Stimulator

DUAL SIMULTANEOUS FUNCTION: TISSUE HEALING AND PAIN BLOCKING

  • The WMcAMP Stimulator is the first electrotherapy device in the world that directly boosts a key molecular signaling system inside cells that relays the body's messages to carry out metabolic activity for healing and tissue regeneration—the Cyclic AMP (cAMP) 'signal transduction pathway'.

    The nerve tissue regeneration effects of elevating cAMP via biochemical intervention are well known. The WMcAMP Stimulator is the first electromedical approach that achieves this result. Supporting research>



Pain Signal Transmitted from the 'Voltage-Gated' Ion Channels through the Pain Nerve Cell Walls


  • Pain occurs when pain nerve cells ('neurons') are signalling along nerve fibres to the brain that injury exists and/or that there is a danger of injury to tissues of the body. The outgoing pain signals start from the inside-to-outside 'voltage-gated' ion channels through the neuron walls.

  • By directly modulating the same cAMP signaling system, the WMcAMP Stimulator also decreases the electrical voltage across the neuron wall ion channels and their overall activity—reducing or stopping the transmission of pain signals.

  • The WMcAMP Stimulator does not 'cover up' the natural pain-generating process; it modulates the pain-generating conditions within the injured tissues—to enhance actual healing and regeneration.


ELECTROTHERAPY CHALLENGES FOR INJURIES

  • The healing process in response to an injury is fantastically complex, involving hundreds of millions of cells. Each cell performs a unique and specialized function to repair and regenerate the injured tissues, in moment-by-moment constantly changing coordination with every other cell.

    There is no way to know what each cell involved in the healing process is doing moment-by-moment.


  • No two injuries are the same; every injury, even of the same anatomical structure, is a unique occurrence in each person, requiring their body's precisely coordinated, unique healing response.

    Most electrotherapy devices for pain or injury treatment, transmit electrical waveforms into the body that is a 'blanket' of stimulation. Some cellular metabolic activity can be temporarily enhanced as a result, while other functions can be negatively interfered with or inhibited at the same time.



WMcAMP STIMULATOR APPROACH: DIRECTLY BOOST WHAT THE BODY IS ALREADY DOING

  • Cyclic AMP (cAMP) is a major and key 'second messenger' molecule inside cells. Following injury, cAMP relays the messages to activate and continue many metabolic events for tissue healing and regeneration, down to the level of gene expression. cAMP is the most well studied second messenger molecule in biological and medical science.


  • Cyclic-A-M-P is produced within cells from the A-T-P molecule. A-T-P is called the "energy currency" of life, it functions like a rechargeable battery, and is the energy source that all cells need in order to do anything within the human body. In response to injury, A-T-P is converted in a repeating cycle into cyclic-A-M-P (cAMP); the cAMP molecules then relay the specific messages to carry out the healing processes for the injury.




Cyclic AMP (cAMP) Second Messenger Activation in Response to Injury



  • The WMcAMP Stimulator precisely targets and gives an electrical energy boost that directly increases production of the cAMP molecule, and then directly increases the activity of the cAMP 'messenger pathways' that are activated in specific response to the injury.


  • The WMcAMP Stimulator generates a repeating, timed, complex stimulation cycle that enhances and is in sync with the natural cAMP events inside the cells of the body.


    The powerful and beneficial effects of the WMcAMP Stimulator for pain and injured tissue healing and regeneration, are well-studied biological and medical science. Supporting research>



DEVELOPMENT

  • The Woessner-Malter Cyclic AMP (WMcAMP) Stimulator has been developed from special cooperation between American Physiatrist (pain and injury rehabilitation specialist physician) and Scientist, Doctor James Woessner MD PhD, and the Electromedicine Clinic in Melbourne, Australia. Dr. Woessner has pioneered and performed nearly 4000 noninvasive electrical nerve block treatments, which he recognized were simultaneously actually repairing damaged pain nerves via cAMP activation. Vita of Dr James Woessner MD PhD>




Damaged Nerve Fibers (red) Within a Nerve Bundle: Targets for cAMP Mediated Regeneration


  • The WMcAMP Stimulator is the result of data-based development, in parallel with laboratory equipment validation and clinical testing.


    The WMcAMP Stimulator has been designed for use by both clinicians and at home.


CYCLIC AMP UTILIZATION EFFECTS

  • Neuron 'blockade'—cAMP directly affects the electrical voltage across the pain nerve cell (neuron) 'voltage-gated' channels, so that neuropathic pain signals reduce or stop.


  • Relays the messages to begin and continue the metabolic activity for healing—down to gene expression.


  • Increases neuron and tissue survival and regeneration following injury.


  • Controls the ability of nerve cell 'axons' (sensing and movement signal conductors) to regenerate after injury.


  • Immune and non-immune system anti-inflammatory effects.


  • Local circulation enhancement.


  • Reduces muscle tension, and exerts central nervous system antispastic actions after injury.


  • Functional stimulation and regeneration of muscles and nerves.


  • Immediate and longer-term injured tissue protection.


  • Enhances whole brain and brain cell connection (synapse) plasticity following injury.


PAIN & INJURY

  • Neuropathic pain blocking. Decreases the overall activity, and the 'action potential' electrical voltage, of pain nerve cell 'voltage-gated' ion channels—reducing or stopping the transmission of pain signals.

  • Enhanced and faster injury healing. Gives extra electrical energy directly to the production and utilization of the 'cAMP' molecular 'messenger pathways' inside cells—that signal to start and continue the metabolic activity for healing, including gene expression.

  • Increased nerve cell and axon survival and regeneration ('neurogenesis') after injury. Prevention of future neuropathic pain and loss of function.

  • Anti-inflammatory. Favorably modulates both immune and non-immune system inflammatory processes—protects injured tissues from chronic degradation.

  • Local circulation enhancement.

  • Reduces muscle tension. Enhances function and regeneration of muscles following injury.

  • Improves whole brain response to injury. Enhanced brain cell connection ('synapse') plasticity after injury.

  • Noninvasive and without drug side effects.

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