WM Cyclic AMP Stimulator

DUAL SIMULTANEOUS FUNCTION: TISSUE HEALING AND PAIN BLOCKING

  • The WMcAMP Stimulator is the first electrotherapy device in the world that directly boosts a key molecular signaling system inside cells that relays the body's messages to start metabolic activity for healing—the Cyclic AMP (cAMP) 'signal transduction pathway'.



Pain Signal Transmitted from the 'Voltage-Gated' Channels through the Pain Nerve Cell Walls


  • Pain occurs when pain nerve cells ('neurons') are signalling along nerve fibres to the brain that injury exists and/or that there is a danger of injury to tissues of the body. The outgoing pain signals start from the inside-to-outside 'voltage-gated' ion channels through the neuron walls.

  • By directly modulating the same cAMP signaling system, the WMcAMP Stimulator also decreases the electrical voltage across the neuron wall ion channels and their overall activity—reducing or stopping the transmission of pain signals. Supporting research>

  • The WMcAMP Stimulator does not 'cover up' the natural pain process generated by the body in response to injury; the WMcAMP Stimulator favorably modulates the pain-generating conditions within the injured tissue 'microenvironments'.


CHALLENGES OF ELECTRICAL STIMULATION FOR PAIN AND INJURY TREATMENT

  • The healing processes in response to an injury are fanastically complex, involving millions of cells. Each cell individually performs a specialized function to repair and regenerate the injured tissues, in moment-by-moment constantly changing coordination with every other cell.


  • No two injuries are the same; every injury even in the same anatomical location, is a unique occurrence in each human being, needing a precisely coordinated, unique healing response from the body.


    Most existing electro-stimulators applied for pain blocking or injury rehabilitation, transmit electrical waveforms in a 'blanket' of electrical stimulation that reaches all cells of the body in range of the electrical power of the device. This blanket electrical stimulation has the same impact on each of the millions of cells of the body, irrespective of what dedicated work in the healing process each individual cell is working to achieve. Some of these cellular functions can be temporarily enhanced by the blanket electrical stimulation, while other functions will be negatively interfered with or inhibited.



WMcAMP STIMULATOR APPROACH: DIRECTLY BOOST WHAT THE BODY IS ALREADY DOING

  • Cyclic AMP (cAMP) is a major and key 'second messenger' molecule inside cells. Following injury, cAMP relays the messages to activate and continue many metabolic events for tissue healing and regeneration, including gene expression. cAMP is the most well studied second messenger molecule in biological and medical science.


  • c-A-M-P is produced directly from the A-T-P molecule. ATP is called the "energy currency" of life, because it is the energy molecule that all cells need in order to do anything within the human body. ATP is used like a rechargeable battery within cells. In response to injury, ATP is converted in a repeating cycle into cAMP, which then forwards the messages to carry out the healing processes.




Cyclic AMP (cAMP) Second Messenger Pathways in Response to Injury



  • The WMcAMP Stimulator precisely targets, and gives an electrical energy boost that directly increases the production itself of the cAMP molecule, and then directly increases activation of the cAMP 'messenger pathways'—which relay the moment-by-moment 'decision-making' signals inside each cell to carry out their specialized functions needed for tissue healing and regeneration in response to a specific injury.


  • The WMcAMP Stimulator generates a repeating, complex stimulation cycle that enhances and is in sync with the natural cAMP events inside the cells of the body.


    The powerful and beneficial effects of the WMcAMP Stimulator for pain and injured tissue healing and regeneration, are well-studied biological and medical science. Supporting research>



DEVELOPMENT

  • The Woessner-Malter Cyclic AMP (WMcAMP) Stimulator has been developed from special cooperation between American Physiatrist (pain and injury rehabilitation specialist physician) and Scientist, Doctor James Woessner MD PhD, and the Electromedicine Clinic in Melbourne, Australia. Dr. Woessner has pioneered and performed nearly 4000 noninvasive electrical nerve block treatments, which he recognized were simultaneously actually repairing damaged pain nerves via cAMP activation. Vita of Dr James Woessner MD PhD>




Damaged Nerve Fibers (red) Within a Nerve Bundle: Targets for cAMP Mediated Regeneration


  • The WMcAMP Stimulator is the result of data-based development, in parallel with laboratory equipment validation and clinical testing.


    The WMcAMP Stimulator has been designed for use by both clinicians and non healthcare professionals.


CYCLIC AMP UTILIZATION EFFECTS

  • Neuron 'blockade'—cAMP directly affects the electrical voltage across the pain nerve cell (neuron) 'voltage-gated' channels, so that neuropathic pain signals reduce or stop.


  • Relays the messages to begin and continue the metabolic activity for healing—down to gene expression.


  • Increases neuron and tissue survival and regeneration following injury.


  • Controls the ability of nerve cell 'axons' (sensing and movement signal conductors) to regenerate after injury.


  • Immune and non-immune system anti-inflammatory effects.


  • Local circulation enhancement.


  • Reduces muscle tension, and exerts central nervous system antispastic actions after injury.


  • Functional stimulation and regeneration of muscles and nerves.


  • Immediate and longer-term injured tissue protection.


  • Enhances whole brain and brain cell connection (synapse) plasticity following injury.


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